Tetrahedron Letters p. 339 - 342 (1998)
Update date:2022-08-29
Topics:
Guindon, Yvan
Denis, Real C.
The efficiency of a tandem process featuring an oxy radical cyclization and hydrogen transfer reaction of the resultant carbon-based radical has been demonstrated. This methodology affords 2,3-trans-disubstituted tetrahydrofurans by creating two new contiguous stereogenic centers with high levels of 1,2-induction in each step.
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