Synthesis p. 485 - 486 (1988)
Update date:2022-08-10
Topics:
Sakamoto, Takao
Nishimura, Sumiko
Kondo, Yoshinori
Yamanaka, Hiroshi
The reaction of N-heteroaryl halides with ω-ethoxycarbonyl-, and ω-chloroalkylzinc iodides, prepared from the corresponding alkyl iodides with zinc-copper couple, in the presence of dichlorobis(triphenylphosphine)palladium in N,N-dimethylacetamide/benzene yielded C-(ω-ethoxycarbonyl)- and C-(ω-chloroalkyl)-N-heteroarenes.
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