The synthesis of optically active pyridyl alcohols from the corresponding racemates by Catharanthus roseus cell cultures

Article abstract of DOI:10.1016/0957-4166(95)00388-6

A novel method for producing optically active pyridyl alcohols 1a-f from the corresponding racemates was developed. When racemic 3-pyridylphenylmethanol 1b is reacted with Catharanthus roseus cell cultures, (-)-1b is obtained in 96% yield with 100% ee.