
Chemical Communications p. 12353 - 12356 (2018)
Update date:2022-08-11
Topics:
Singh, Hardev
Kim, Seo Jin
Kang, Dong Hoon
Kim, Hye-Ri
Sharma, Amit
Kim, Won Young
Kang, Chulhun
Kim, Jong Seung
Herein, we report the potential of glycyrrhetinic acid (GA) as an active targeting ligand for hepatocellular carcinoma (HCC) for the development of diagnosis/therapy using small-molecule based approaches. Our preliminary results demonstrated that GA-conjugation to diagnostic/therapeutic counterparts significantly enhanced their HCC targeting ability and excellent therapeutic efficacy.
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Doi:10.1007/BF00972745
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