A convenient synthesis of glycals employing in-situ generated Cp2TiCl

Article abstract of DOI:10.1016/S0040-4039(99)01266-6

Reductive elimination of acetylated glycosyl bromides to the corresponding glycal is easily achieved by mixing the bromide with Cp₂TiCl₂ and Mn in THF, and hence does not require the separate preparation of Cp₂TiCl using glove-box techniques.