An efficient general synthesis of squarate esters

Article abstract of DOI:10.1080/00397919708006826

An efficient and general method for the synthesis of alkyl squarates is presented. This involves the reactions of squaric acid with the desired alcohol in the presence of an orthoformate. This was applicable for the synthesis of dimethyl-, diethyl-, diisopropyl, di-n-butyl and di-t-butyl squarates in yields ranging from 77-97%. It is a convenient and safe method that can be accomplished on a multigram scale.

Full text of DOI:10.1080/00397919708006826

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Synthetic Communications: An
International Journal for Rapid
Communication of Synthetic
Organic Chemistry
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An Efficient General Synthesis
of Squarate Esters
Hiu Liu a , Craig S. Tomooka a & Harold W. Moore a
a Department of Chemistry, University of California,
Irvine, CA, 92717
Version of record first published: 22 Aug 2006.
To cite this article: Hiu Liu, Craig S. Tomooka & Harold W. Moore (1997): An Efficient
General Synthesis of Squarate Esters, Synthetic Communications: An International
Journal for Rapid Communication of Synthetic Organic Chemistry, 27:12, 2177-2180
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