Lead tetraacetate cleavage of chiral phenylglycinol derived secondary amines without racemization

Article abstract of DOI:10.1080/00397919308009866

Diastereomerically enriched N-(1,1-disubstituted methyl)(2'-hydroxy-1'-phenylethyl)amines were oxidatively converted to enantiomerically enriched primary disubstituted methylamines in excellent yields without racemization, using an improved lead tetraacetate (LTA) procedure.

Full text of DOI:10.1080/00397919308009866

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Synthetic Communications: An
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Lead Tetraacetate Cleavage of
Chiral Phenylglycinol Derived
Secondary Amines Without
Racemization
Mohamed K. Mokhallalati a & Lendon N. Pridgen a
a Synthetic Chemistry Department , Smith Kline
Beecham Pharmaceuticals , Post Office Box 1539,
King of Prussia, PA 19406-0939
Published online: 16 Feb 2007.
To cite this article: Mohamed K. Mokhallalati & Lendon N. Pridgen (1993)
Lead Tetraacetate Cleavage of Chiral Phenylglycinol Derived Secondary Amines
Without Racemization, Synthetic Communications: An International Journal for
Rapid Communication of Synthetic Organic Chemistry, 23:14, 2055-2064, DOI:
10.1080/00397919308009866
To link to this article: http://dx.doi.org/10.1080/00397919308009866
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