Catalytic single-chain antibodies possessing β-lactamase activity selected from a phage displayed combinatorial library using a mechanism-based inhibitor

DOI: 10.1016/S0040-4039(99)01695-0

Source and publish data:

Tetrahedron Letters p. 8063 - 8066 (1999)

Update date:2022-08-11

Topics:

Authors:

Tanaka, Fujie

Almer, Helena

Lerner, Richard A.

Barbas III, Carlos F.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(99)01695-0

Catalytic single-chain antibodies (scFvs) possessing β-lactamase activity were selected from a phage displayed combinatorial antibody library using a penam sulfone mechanism-based inhibitor of β-lactamase. The scFvs FT6 and FT12 catalyzed the hydrolysis o

Full text of DOI:10.1016/S0040-4039(99)01695-0

Products guided by the article

Product name:[2R-[2α[R*(R*)],4β]]-α-[(AMinophenylacetyl)aMino]-4-carboxy-5,5-diMethyl-2

Cas No:32746-94-4

R&D Labs maybe for 32746-94-4

LIAOYANG WANRONG CHEMICALS COMPANY LIMITED

Contact:86-419-2390789

Address:XINLI VILLAGE , DONG NINGWEI COUNTY,TAIZIHE DISTRICT, LIAOYANG , LIAONING
Hubei Honch Pharmaceutical Co.,Ltd

Contact:86-713-7222018

Address:Li Shizhen Pharmaceutical Industry park, Qichun County, Hubei Province,China
suzhou chukai pharmateach co,.ltd

Contact:86-512-88812511

Address:Building 3, Wujiang Scientific Innovation Park, 2358 Changan Rd, Wujiang 215200, Jiangsu Province, P. R. China
Frapp's Chemical (NFTZ) Co.,Ltd

Contact:+86-576-86137892

Address:General Chamber of Commercial Building, 159 Wanchang Middle Road, Wenling, Zhejiang, China
Xi'an Tizan Tech & Industry Co., Ltd.

Contact:86-18629066522

Address:C3009 TANG FENG INTERNATIONAL PLAZA, NO.18 FENGHUI NAN ROAD, XI'AN HIGH TECH ZONE, 710075 CHINA.

Relevant to this article

Preparation of ethyl (R)-3-hydroxy-4-chlorobutyrate by selective reduction of (R)-4-(trichloromethyl)-oxetan-2-one: Key intermediate to (R)-carnitine and (R)-4-amino-3-hydroxybutyric acid

Doi:10.1080/00397919708003044
(1997)
Acid esters of triterpenoids and steroid glycosides from Gambeya africana

Doi:10.1055/s-2002-34416
(2002)
Production of monocyclic phenols by the liquid-phase hydrogenolysis of benzofuran and dibenzyl ether using in situ hydrogen production from methanol

Doi:10.1016/j.cattod.2017.08.018
(2018)
Sensitization-initiated electron transferviaupconversion: mechanism and photocatalytic applications

Doi:10.1039/d1sc02085d
(2021)
Doi:10.1007/s11745-001-0742-4
(1892)
A novel approach towards design, synthesis and evaluation of some Schiff base analogues of 2-aminopyridine and 2-aminobezothiazole against hepatocellular carcinoma

Doi:10.1016/j.biopha.2017.01.108
(2017)

Article Doi