Tetrahedron Letters p. 169 - 170 (1994)
Update date:2022-08-11
Topics:
Cucciolito
Cucciolito, Maria E.
Ruffo
Ruffo, Francesco
Vitagliano
Vitagliano, Aldo
Funicello, Maria
By using the Corey diamine 1,2-diphenyl-N,N'-bis[(2,4,6- trimethylphenyl)methyl]-1,2-diaminoethane, Copper(I) olefin complexes are prepared. When the olefin is a racemic allylic alcohol, selective coordination of one enantiomer is observed. Cleavage with aqueous HCl or NaCN allows a two-steps resolution affording excellent enantiomeric excess.
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