Analysis of conjugated bile acids in human biological fluids. Synthesis of hyodeoxycholic acid 3- and 6-glycosides and related compounds

DOI: 10.1248/cpb.42.1479

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 1479 - 1484 (1994)

Update date:2022-08-10

Topics:

Authors:

Iida Iida

Tazawa Tazawa

Ohshima Ohshima

Niwa Niwa

Goto Goto

Nambara Nambara

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1248/cpb.42.1479

The glucuronide, glucoside and N-acetylglucosaminide conjugates of hyodeoxycholic acid were synthesized. In addition, murideoxycholic acid 3- glycosides and some of their C-5 epimeric analogs were also prepared. The principal reactions used are 1) the Koenigs-Knorr condensation reaction of 3- oxo-6α-hydroxy and 6-oxo-3α-hydroxy esters with an appropriate α- acetohalosugar catalyzed by cadmium carbonate in benzene under reflux, 2) reduction of the resulting bile acid glycoside methyl ester-acetates with tert-butylamine-borane complex, and 3) subsequent hydrolysis with aqueous lithium hydroxide.

Full text of DOI:10.1248/cpb.42.1479

NII-Electronic Library Service

Products guided by the article

Product name:(5β,6α)-6-Hydroxy-3-oxo-cholan-24-oic Acid Methyl Ester

Cas No:3360-89-2

R&D Labs maybe for 3360-89-2

X.T.Y Environ-Tech Co.,Ltd

Contact:+86-310-7092106

Address:Quzhou Modern & New Industrial Park, Handan, Hebei 057250, China
Mollt Biochem Co., Ltd(expird)

Contact:+86-21-38682181

Address:shanghai ,china
Nanjing Fayekong Chemcial Co.,Ltd(expird)

Contact:86-25-58813444

Address:Rm 1503, Unit 1, Building 5, Zijinnanyuan, Nanjing, Jiangsu, China
Jurong Huaheng Natural Biological Products Factory

website:http://www.risebiochem.com

Contact:+86-13921007726

Address:Chuncheng town,Jurong city,Jiangsu province,China
Zhejiang Quzhou Jiancheng Silicone Co., Ltd.(Shanghai Jiancheng Industial and Trade Co, Ltd)

Contact:18957018777 +86-570-3888777

Address:The company production base address： Quzhou City, Zhejiang Province high-tech industrial park Nianhua Road 37

Relevant to this article

Synthesis and Antiviral Activity Evaluation of 2′,5′,5′-Trifluoro-Apiosyl Nucleoside Phosphonic Acid Analogs

Doi:10.1080/15257770.2015.1115522
(2016)
Photochemical studies LII: investigation on the photostability of testosterone and methyltestosterone in the solid state

Doi:10.1002/ardp.19893220311
(1989)
Regioselective iodination of phenol and analogues using N-iodosuccinimide and p-toluenesulfonic acid

Doi:10.1016/j.tetlet.2009.03.128
(2009)
Synthesis of Substituted 3(2H)-Furanones Using Alkylative Intramolecular Cyclization of Sulfonium Salts

Doi:10.1021/acs.joc.6b01528
(2016)
Thio effects on the departure of the 3′-linked ribonucleoside from diribonucleoside 3′,3′-phosphorodithioate diesters and triribonucleoside 3′,3′,5′-phosphoromonothioate triesters: Implications for ribozyme catalysis

Doi:10.1002/chem.200601835
(2007)
Functionalization on silica gel with allylsilanes. A new method of covalent attachment of organic functional groups on silica gel

Doi:10.1021/ja034691l
(2003)

Article Doi