A simple, general and efficient method for O and N-retinoylation. Application to the synthesis of 2-retinoyl-lecithin

Article abstract of DOI:10.1080/00397919808004874

The synthesis of the new 1-stearoyl-2-retinoyl-glycero-3- phosphorylcholine by coupling of retinoic acid and lysolecithin with DCC- DMAP (1.2 eq.) is reported. This method is applied to O and N-retinoylation of uncharged organic substrates such as aliphatic alcohols, free hydroxyl anomeric sugars, aromatic amines and C-protected α-aminoacids.

Full text of DOI:10.1080/00397919808004874

Synthetic Communications
ISSN: 0039-7911 (Print) 1532-2432 (Online) Journal homepage: http://www.tandfonline.com/loi/lsyc20
A Simple, General and Efficient Method for O and
N-Retinoylation. Application to The Synthesis of 2-
Retinoyl-Lecithin
Charles Sangmam , Jean-Yves Winum , Marc Lucas , Jean-Louis Montero &
Claude Chavis
To cite this article: Charles Sangmam , Jean-Yves Winum , Marc Lucas , Jean-Louis Montero
& Claude Chavis (1998) A Simple, General and Efficient Method for O and N-Retinoylation.
Application to The Synthesis of 2-Retinoyl-Lecithin, Synthetic Communications, 28:16,
2945-2958, DOI: 10.1080/00397919808004874
To link to this article: http://dx.doi.org/10.1080/00397919808004874
Published online: 23 Aug 2006.
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Date: 04 June 2016, At: 13:08