Stereoselective reduction of α,β-epoxy ketones with sodium borohydride in the presence of calcium chloride or lanthanum chloride. A practical preparation of erythro-α,β-epoxy alcohols

Article abstract of DOI:10.1016/0040-4020(94)00967-Y

erythro-Epoxy alcohols were prepared with high stereoselectivity by NaBH₄ reduction of the corresponding α,β-epoxy ketones in the presence of calcium chloride or lanthanum chloride regardless of the substituents on the epoxide ring.