A CONVENIENT TRIFLUOROMETHYLATION OF AROMATIC HALIDES WITH SODIUM TRIFLUOROACETATE

DOI: 10.1246/cl.1981.1719

Source and publish data:

Chemistry Letters p. 1719 - 1720 (1981)

Update date:2022-08-23

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Authors:

Matsui, Kiyohide

Tobita, Etsuko

Ando, Midori

Kondo, Kiyosi

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Article abstract of DOI:10.1246/cl.1981.1719

Regiospecific trifluoromethylation by substitution of the halogen in aromatic halides was achieved by the use of sodium trifluoroacetate and copper(I) iodide.The reaction proceeded smoothly in dipolar aprotic solvents in good to high yields.

Full text of DOI:10.1246/cl.1981.1719

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