Trifluoroacetylation of methylpyridines and other methylazines: A convenient access to trifluoroacetonylazines

DOI: 10.3987/COM-98-8268

Source and publish data:

Heterocycles p. 2103 - 2109 (1998)

Update date:2022-08-10

Topics:

Authors:

Kawase, Masami

Teshima, Mutsumi

Saito, Setsuo

Tani, Satoru

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Article abstract of DOI:10.3987/COM-98-8268

Treatment of methyl substituted azines, such as pyridine, pyrimidine, quinoline, oxazole, benzoxazole, benzimidazole, and benzothiazole, with trifluoroacetic anhydride in the presence of pyridine at room temperature gave the corresponding trifluoroacetonyl substituted azines in good yields.

Full text of DOI:10.3987/COM-98-8268

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