Microbiological transformations 37. An enantioconvergent synthesis of the β-blocker (R)-Nifenalol using a combined chemoenzymatic approach

DOI: 10.1016/S0040-4020(97)00639-X

Source and publish data:

Tetrahedron p. 9707 - 9714 (1997)

Update date:2022-08-25

Topics:

Authors:

Pedragosa-Moreau

Morisseau

Baratti Baratti

Zylber Zylber

Archelas

Furstoss

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Article abstract of DOI:10.1016/S0040-4020(97)00639-X

This work describes the synthesis of (R)-Nifenalol based on an enantioconvergent chemoenzymatic hydrolysis of para-nitrostyrene oxide. A mathematical approach is devised which allowed to optimize the process.

Full text of DOI:10.1016/S0040-4020(97)00639-X

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