The reaction of isatin with alkoxycarbonylmethylene (triphenyl)phosphoranes

Article abstract of DOI:10.1080/10426509808545485

Isalin (1) reacted with alkoxycarbonylmethylene(triphenyl)phosphoranes (2) in boiling benzene for about 3 h to give orange yellow crystalline products of alkyl (1,2-dihydro-2-oxo-3H-indol-3-yl)acetates (3). The double bond of compounds 3 was reduced with zinc dust in boiling acetic acid to give 5, which upon methylation with methyl iodide in dry acetone and anhydrous potassium carbonate yielded the corresponding products 6. The structural assignments of the new compounds are based on the spectroscopic results.

Full text of DOI:10.1080/10426509808545485

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Phosphorus, Sulfur, and
Silicon and the Related
Elements
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The Reaction
of Isatin with
Alkoxycarbonylmethylene
(
Triphenyl)Phosphoranes
Fayez H. Osman & Fatma A. El-Samahy
a
Department of Pesticide Chemistry,
National Research Center, Dokki, Cairo
1
2622, Egypt
b
Department of Pesticide Chemistry,
National Research Center, Dokki, Cairo
2622, Egypt
Version of record first published: 17 Mar
008.
1
2
To cite this article: Fayez H. Osman & Fatma A. El-Samahy (1998): The
Reaction of Isatin with Alkoxycarbonylmethylene (Triphenyl)Phosphoranes,
Phosphorus, Sulfur, and Silicon and the Related Elements, 134:1, 437-446
To link to this article: http://dx.doi.org/10.1080/10426509808545485
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