A facile route to 3-alkoxy-2-methylpropenals, useful intermediates in the synthesis of carotenoids

Article abstract of DOI:10.1080/00397919608003549

A 'one-pot' process for the preparation of a carotenoid synthon (4) has been developed that involves methoxide-promoted condensation of propionaldehyde with methyl formate, followed by exclusive O-alkylation of the resultant stabilized enolate (6).

Full text of DOI:10.1080/00397919608003549

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Synthetic Communications: An
International Journal for Rapid
Communication of Synthetic
Organic Chemistry
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A Facile Route to 3-Alkoxy-2-
methylpropenals, Useful
Intermediates in the Synthesis
of Carotenoids
a
a
James H. Babler , Vincent P. Liptak , Jeffrey A.
a
a
Trautmann & Gregory H. Zayia
a
Department of Chemistry , Loyola University of
Chicago , Chicago, IL, 60626, U.S.A.
Published online: 21 Aug 2006.
To cite this article: James H. Babler , Vincent P. Liptak , Jeffrey A. Trautmann
&
Gregory H. Zayia (1996) A Facile Route to 3-Alkoxy-2-methylpropenals, Useful
Intermediates in the Synthesis of Carotenoids, Synthetic Communications: An
International Journal for Rapid Communication of Synthetic Organic Chemistry, 26:10,
1943-1951, DOI: 10.1080/00397919608003549
To link to this article: http://dx.doi.org/10.1080/00397919608003549
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