A METHOD FOR THE SYSTEMATIC RESOLUTION OF UNBRANCHED α-ACETOXYALKYL- AND ARALKYLALDEHYDES: SYNTHESIS OF 11R AND 11S-HETE

DOI: 10.1016/S0040-4039(00)87322-0

Source and publish data:

Tetrahedron Letters p. 2285 - 2288 (1982)

Update date:2022-08-30

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Authors:

Just, George

Luthe, Corinne

Potvin, Pierre

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Article abstract of DOI:10.1016/S0040-4039(00)87322-0

It is shown that oxazolidines derived from racemic unbranched α-acetoxyaldehydes and l-ephedrine have predictable chromatographic mobilities, with the R-isomer always having a higher R_f-value.This resolution has been used to prepare 11R and 11S-HETE.

Full text of DOI:10.1016/S0040-4039(00)87322-0

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