EFFICIENT INDIRECT ELECTROCHEMICAL IN-SITU REGENERATION OF NADH: ELECTROCHEMICALLY DRIVEN ENZYMATIC REDUCTION OF PYRUVATE CATALYZED BY D-LDH

Article abstract of DOI:10.1016/S0040-4039(00)96919-3

Using Cl (1) as redox catalyst for the continous NADH regeneration it was possible to perform an electrochemically driven enzymatic reduction of pyruvate to D-lactate catalyzed by D-LDH at a rate of 5 turnovers per hour.This is by a factor of 20 faster than the best results obtained until now.Current yields of 50 to 70 percent may be obtained.