LACK OF GLYCOSIDASE INHIBITION BY, AND ISOLATION FROM XANTHOCERCIS ZAMBESIACA (LEGUMINOSAE) OF, 4-O-(&β-D-GLUCOPYRANOSYL)-FAGOMINE , A NOVEL GLUCOSIDE OF POLYHYDROXYLATED PIPERIDINE ALKALOID

Article abstract of DOI:10.1016/S0040-4039(00)99072-5

A COSY spectrum has been used to determine the position of inter-residue linkage in 4-O-(β-D-glucopyranosyl) fagomine (1) an example of a new class of glycosides of polyhydroxylated piperidine alkaloids isolated from seed of the legume Xanthocercis zambesiaca. (Bak.) Dunn.Unlike a number of polyhydroxylated piperidines, neither the glucoside (1) nor the fagomine <1,2,5-trideoxy-1,5-imino-D-arabitohexitol> (3) showed any inhibitory activity towards glycosidase enzymes from a variety of sources.