Journal of the Chemical Society. Perkin transactions I p. 553 - 560 (1992)
Update date:2022-08-24
Topics:
Cooper, Jeremy
Knight, David W.
Gallagher, Peter T.
N-Alkylation of the β-amino acid derivative 16, derived from (L)-aspartic acid, by the allylic chloride 12b followed by deprotection and lactonization leads to the nine-membered azalactone 18.Enolate Claisen rearrangement of this leads stereospecifically, via a boat-like transition state (cf. 6), to the pyrrolidine acid 19; subsequent one-carbon homologation, oxidation and deprotection affords (-)-(α)-kainic acid 1.
View MoreSJZ Chenghui Chemical Co., Ltd.
Contact:86-311-87713916
Address:no.368 youyi north avenue
JiangXi Hong Run Chemical Co., Ltd
Contact:+86-0791-88521351
Address:XingHuo industrial zone in YongXiu county
Hebei Kangtai Pharmaceutical Co.,Ltd
Contact:+86-0317-3512963
Address:Wugang Road,Mengcun of Cangzhou City,Hebei Province ,China
Contact:+86-571-87859231, 87859237, 87859239
Address:1606,Huarong Times Mansion, No.3880 Jiangnan Avenue, Binjiang District, Hangzhou, China, 310053
Yancheng Smiling Imp & Exp Co., Ltd.
Contact:+86-515-83173586
Address:Rm1207, BLD#03, Phoenix Plaza, Juheng Road, Yancheng, Jiangsu, P.R. China
Doi:10.1039/c3nj00285c
(2013)Doi:10.1021/ja01126a029
(1952)Doi:10.1002/hlca.19860690514
(1986)Doi:10.1039/c2dt30198a
(2012)Doi:10.1080/00304948.2016.1194130
(2016)Doi:10.1016/j.tetlet.2009.05.103
(2009)
