APPLICATION OF DIMETHYLSULFOXIDE(DMSO)/TRIFLUOROACETIC ACID(TFA) OXIDATION TO THE SYNTHESIS OF CYSTINE-CONTAINING PEPTIDE

DOI: 10.1016/S0040-4039(00)92050-1

Source and publish data:

Tetrahedron Letters p. 1223 - 1226 (1991)

Update date:2022-08-24

Topics:

Authors:

Otaka, Akira

Koide, Takaki

Shide, Atsuko

Fujii, Nobutaka

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Article abstract of DOI:10.1016/S0040-4039(00)92050-1

S-protected cysteine derivatives as well as cysteine were converted to cystine by action of DMSO/TFA; as examples, two model peptides, oxytocin and an α-human calcitonin gene-related peptide (α-hCGRP), were prepared by this reaction.

Full text of DOI:10.1016/S0040-4039(00)92050-1

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