Mild deprotection of methyl, benzyl, methoxymethyl, methylthiomethyl, methoxyethoxymethyl, and β-(trimethylsilyl)ethoxymethyl esters with AlCl3- N,N-dimethylaniline

Article abstract of DOI:10.1080/00397919408010233

Methyl, benzyl, methoxymethyl, methylthiomethyl, methoxyethoxymethyl, and β-(trimethylsilyl)ethoxymethyl esters could be cleaved readily under mild conditions on treatment with AlCl₃-N,N-dimethylaniline in CH₂Cl₂ to give parent carboxylic acids in high yields.

Full text of DOI:10.1080/00397919408010233

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Synthetic Communications: An
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Mild Deprotection of Methyl,
Benzyl, Methoxymethyl,
Methylthiomethyl,
Methoxyethoxymethyl, and β-
(Trimethylsilyl)-ethoxymethyl
Esters with AlCl -N,N-
3
dimethylaniline
a
a
Takahiko Akiyama , Hajimu Hirofuji , Akiko Hirose
a
a
&
Shoichiro Ozaki
a
Department of Applied Chemistry , Faculty
of Engineering, Ehime University, Bunkyo-cho ,
Matsuyama, 790, Japan
Published online: 23 Sep 2006.
To cite this article: Takahiko Akiyama , Hajimu Hirofuji , Akiko Hirose & Shoichiro
Ozaki (1994) Mild Deprotection of Methyl, Benzyl, Methoxymethyl, Methylthiomethyl,
Methoxyethoxymethyl, and β-(Trimethylsilyl)-ethoxymethyl Esters with AlCl3-
N,N-dimethylaniline, Synthetic Communications: An International Journal for
Rapid Communication of Synthetic Organic Chemistry, 24:15, 2179-2185, DOI:
10.1080/00397919408010233
To link to this article: http://dx.doi.org/10.1080/00397919408010233
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