The first enantioselective syntheses of pure R- and S-isoproterenol

Article abstract of DOI:10.1016/S0040-4039(00)94578-7

An efficient and highly selective synthetic route to either R- or S-isoproterenol (1) is described which employs a robot-like catalytic molecule to establish chirality, and readily provides these important therapeutic agents in enantiomerically pure form.