A SIMPLE ORGANOCOBALT MEDIATED SYNTHESIS OF SUBSTITUTED 3-OXABICYCLOOCT-6-EN-7-ONES

Article abstract of DOI:10.1016/0040-4039(84)80061-1

A range of substituted propargyl alcohols form ethers with allyl bromide in good yields; conversion of these ethers to the alkyne hexacarbonyl dicobalt complexes using Co2(CO)8, followed by intramolecular cyclisation gives substituted 3-oxabicyclo<3.3.0>oct-6-en-7-ones (4a-4e) in fair to moderate yields.