Phytochemistry p. 735 - 738 (1997)
Update date:2022-08-10
Topics:
Takano, Ichiro
Yasuda, Ichiro
Nishijima, Motohiro
Yanagi, Yukiohitotsu
Takeya, Koichi
Itokawa, Hideji
Three alkaloids, neoharringtonine, homoneoharringtonine and 3'S- hydroxyneoharringtonine, were isolated from the leaves and stems of Cephalotaxus harringtonia var. drupacea. Their structures were established by spectroscopic methods, including two-dimensional NMR and CD spectra, and their antileukaemic activity was evaluated using P-388 leukaemia cells.
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