Enamines of 3-acyltetramic acids from β-enamino amides and amino acids

Article abstract of DOI:10.1016/j.tetlet.2017.11.023

A novel approach for the synthesis of enamine derivatives of N-protected 3-acyltetramic acids is described. The synthetic procedure relies on α-C-acylation of β-enamino amides with N-protected α-amino acids and subsequent cyclisation of the obtained inter