
Bulletin of the Chemical Society of Japan p. 4158 - 4160 (1988)
Update date:2022-08-16
Topics:
Shiraiwa, Tadashi
Kataoka, Kazuo
Sakata, Shinji
Kurokawa, Hidemoto
Optically active cysteine (Cys) was racemized via formation of (RS)-2,2-dimethyl-4-thiazolidinecarboxylic acid ((RS)-DMT) by refluxing in the presence of acetone in 10-fold molar amount in acetic acid.The formed (RS)-DMT was hydrolyzed by adding water to the reaction mixture to give (RS)-Cys in 95-97percent yield.
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