Silver-catalyzed heterocyclization: First total synthesis of the naturally occurring cis 2-hexadecyl-3-hydroxy-4-methylene butyrolactone

DOI: 10.1016/S0040-4039(00)73226-6

Source and publish data:

Tetrahedron Letters p. 3525 - 3528 (1994)

Update date:2022-08-11

Topics:

Authors:

Dalla Dalla

Pale Pale

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Article abstract of DOI:10.1016/S0040-4039(00)73226-6

The title compound was obtained in 4 steps with an overall yield of 64% with the silver-catalyzed cyclization of the corresponding substituted β-hydroxy-γ-acetylenic acid as the key step.

Full text of DOI:10.1016/S0040-4039(00)73226-6

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