Fabrication of novel electrochemical reduction systems using alcohol dehydrogenase as a bifunctional electrocatalyst

Article abstract of DOI:10.1246/cl.1996.137

Electrochemical reduction of NADP⁺ to NADPH and of NAD⁺ to NADH with current efficiencies of more than 97% has been achieved at alcohol dehydrogenase (ALDH) in the presence of acctophenone as an electron mediator. Addition of acetone or acctaldehyde as a substrate to the above electrolytic system allowed reduction of the substrate to the corresponding alcohol at ALDH accompanied by oxidation of the resulting NAD(P)H.