Synthesis of 13-Ethyl-11-methylene-18,19-dinor-17α-pregn-4-en-20-yn-17-ol (Desogestrel) and its Main Metabolite 3-Oxo-Desogestrel

DOI: 10.1016/S0040-4020(01)89263-2

Source and publish data:

Tetrahedron p. 10709 - 10720 (1994)

Update date:2022-08-11

Topics:

Authors:

Schwarz, Sigfrid

Ring, Sven

Weber, Gisela

Teichmueller, Gerhard

Palme, Hans-Joachim

et al. et al.

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Article abstract of DOI:10.1016/S0040-4020(01)89263-2

A synthesis of the steroid hormone desogestrel (25) from the 18a-homo steroid 1 is described. 25 was transformed into 3-oxo-desogestrel (28) by allyl oxidation.

Full text of DOI:10.1016/S0040-4020(01)89263-2

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