Chiral t-butylphenylphosphinothioic acid: A useful chiral solvating agent for direct determination of enantiomeric purity of alcohols, thiols, amines, diols, aminoalcohols and related compounds

Article abstract of DOI:10.1016/0957-4166(96)00345-X

Enantiomers of t-butylphenylphosphinothioic acid were found to be useful chiral solvating agents (CSAs) for ¹H-NMR determination of enantiomeric excess (ee) of many classes of chiral organic compounds, such as alcohols, diols, thiols, mercaptoalcohols, amines, aminoalcohols, hydroxyacids and related compounds.