Enzymatic resolution of Z-γ,γ1-di-tert-butyl-D,L-carboxyglutamic acid methyl ester

DOI: 10.1016/0040-4039(95)02175-2

Source and publish data:

Tetrahedron Letters p. 417 - 418 (1996)

Update date:2022-08-11

Topics:

Authors:

Clapes, Pere

Valverde, Isabel

Jaime, Carles

Torres, Josep Lluis

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Article abstract of DOI:10.1016/0040-4039(95)02175-2

A rapid and simple method for the resolution of Z-γ,γ¹-di-tert-butyl-D,L-carboxyglutamic acid methyl ester is described. The new procedure is based on the enzymatic enantioselective saponification of the methyl ester by the endoprotease papain.

Full text of DOI:10.1016/0040-4039(95)02175-2

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