Organic Letters
Letter
for possible anticancer development of this class of
compounds. The biosynthetic mechanisms and physiological
functions of the thioamycolamides in the producing organism
are also of considerable interest because of their highly
modified skeletons.
the Takeda Science Foundation, and The Tokyo Biochemical
Research Foundation to T.K. are greatly appreciated.
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Naoya Shinzato − Tropical Biosphere Research Center,
University of the Ryukyus, Okinawa 903-0213, Japan
Notes
The authors declare no competing financial interest.
ACKNOWLEDGMENTS
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This work was supported in part by a Grant-in Aid for
Scientific Research from the Ministry of Education, Culture,
Sports, Science and Technology, Japan (17H06401 (H.K.),
1
9H02840 (H.K.), 18K14396 (T.K.)), and the Platform
Project for Supporting Drug Discovery and Life Science
Research from AMED, Japan (JP19am0101092 (H.K.)). The
contributions from the SUNBOR GRANT, the Daiichi-Sankyo
Award in The Society of Synthetic Organic Chemistry Japan,
D
Org. Lett. XXXX, XXX, XXX−XXX