Enantiospecific Synthesis of 2-Crotonyloxy-(4R,5R,6R)-4,5,6-trihydroxycyclohex-2-enone (COTC) from Quinic Acid

DOI: 10.1039/c39900000312

Source and publish data:

Journal of the Chemical Society. Chemical communications p. 312 (1990)

Update date:2022-08-29

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Authors:

Shing, Tony K.M.

Tang, Ying

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Article abstract of DOI:10.1039/c39900000312

A thirteen-step synthesis of the glyoxalase I inhibitor COTC (2-crotonyloxy-(4R,5R,6R)-4,5,6-trihydroxycyclohex-2-enone) from quinic acid is described.

Full text of DOI:10.1039/c39900000312

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