LA DEPROTECTION ELECTROCHIMIQUE DES AMINES (II) - PROBLEMES POSES PAR LA COUPURE CATHODIQUE DES p.TOLUENE SULFONAMIDES.

Article abstract of DOI:10.1016/S0040-4020(01)96526-3

The deprotection of amines may be conducted via cathodic clevage of the corresponding sulfonamides.However, the selectivity of the reaction depends on parameters such as the tendency of sulfonamide in the absence of proton donors to be decomposed into imine at the cathodic interface.The problem is discussed as a function of the molecular structure of the starting sulfonamide.Results on simple sulfonamides are applied successfully in the deprotection of polysulfonamides and may allow the synthesis of new polyaza-ligands