Tetrahedron Letters p. 2063 - 2066 (1983)
Update date:2022-08-11
Topics:
Marsden, Richard
MacLean, David B.
The reaction of phthalide anions with 3,4-dihydroisoquinolines yields 13-hydroxy-8-oxotetrahydroprotoberberines with the hydrogen atoms at C-13 and C-14 trans to one another; reduction of the lactams yields the corresponding 13-hydroxytetrahydroprotoberberines.
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