A NEW SYNTHESIS OF THE PROTOBERBERINE SYSTEM

DOI: 10.1016/S0040-4039(00)81844-4

Source and publish data:

Tetrahedron Letters p. 2063 - 2066 (1983)

Update date:2022-08-11

Topics:

Authors:

Marsden, Richard

MacLean, David B.

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Article abstract of DOI:10.1016/S0040-4039(00)81844-4

The reaction of phthalide anions with 3,4-dihydroisoquinolines yields 13-hydroxy-8-oxotetrahydroprotoberberines with the hydrogen atoms at C-13 and C-14 trans to one another; reduction of the lactams yields the corresponding 13-hydroxytetrahydroprotoberberines.

Full text of DOI:10.1016/S0040-4039(00)81844-4

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