5-Formyl-δ-valerolactone: A useful synthon for the chiral synthesis of the vespa Orientalis pheromone and the mosquito oviposition attractant pheromone

Article abstract of DOI:10.1016/S0040-4039(00)74412-1

A synthetic scheme starting from the reaction between the lithiated N-allyl-N-methyl(bisdimethylamino)phosphoramide anion and the triflate derivative of (R)-(-)- or (S)-(+)-2,3-O-isopropylideneglycerol is described to prepare the key chiral synthon (R)-5- or (S)-5-formyl-δ-valerolactone that leads to the title compounds.