Synthesis of Hydroxy Ketones by Chemoselective Alkylation of Keto Aldehydes with Dialkylzincs Catalyzed by Amino Alcohol, Diamine, or Dilithium Salt of Piperazine

Article abstract of DOI:10.1246/bcsj.62.2124

Hydroxy ketones were obtained in high yields by the chemoselective alkylation of formyl group of keto aldehydes with dialkylzincs in the presence of such catalysts as 2-dimethylaminoethanol, N,N,N',N'-tetramethylethylenediamine, ordilithium salt of pipera