Tetrahedron Asymmetry p. 1061 - 1067 (1997)
Update date:2022-08-10
Topics:
Hulsbos, Edith
Marcus, Jan
Brussee, Johannes
Van der Gen, Arne
A new method for the preparation of enantiomerically pure N-benzyl nitrones is described. By using either a one-pot reduction-transimination or a one-pot Grignard addition-transimination sequence chiral O-protected α-hydroxynitriles can be converted into chiral aldo- and ketonitrones, respectively.
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Doi:10.1016/S0022-328X(00)82067-7
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