
Synthesis p. 693 - 694 (1996)
Update date:2022-08-17
Topics:
Reyes, Elba D.
Carballeira, Néstor M.
The biologically intriguing (Z)-15-methylhexadec-11-enoic acid, a component of Myxococcus xanthus and Cyamopsis tetragonolobus, has been synthesized in 19% overall yield via the Wittig reaction of 4-methyl-1-pentyltriphenylphosphonium bromide and 10-bromodecanal. The title compound displayed marginal cytotoxicity against human cervix carcinoma (HeLa) and Chinese hamster ovary (CHO) cells.
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