Journal of Medicinal Chemistry p. 1737 - 1739 (1984)
Update date:2022-08-11
Topics:
Schneller, Stewart W.
Luo, Jiann-Kuan
Hosmane, Ramachandra S.
Clerqu, Erik De
Stoeckler, Johanna D.
et al.
The synthesis of 6-amino-1H-pyrrolo<3,2-c>pyridin-4(5H)-one (3,7-dideazaguanine, 2) has been accomplished from 3-(ethoxycarbonyl)pyrrole-2-acetonitrile.In contrast to 3-deazaguanine, compound 2 did not show any antitumor, antiviral. or antibacterial properties.Furthermore, it was not a substrate for hypoxanthine-guanine phosphoribosyltransferase or purine nucleoside phosphorylase.
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