Selective palladium-mediated synthesis of racemic 4,5-disubstituted 5H- furan-2-ones from 3-ynoic acids and organic halides

DOI: 10.1016/S0040-4039(98)01652-9

Source and publish data:

Tetrahedron Letters p. 7599 - 7602 (1998)

Update date:2022-08-30

Topics:

Authors:

Rossi, Renzo

Bellina, Fabio

Biagetti, Matteo

Mannina, Luisa

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Article abstract of DOI:10.1016/S0040-4039(98)01652-9

Racemic 4,5-disubstitued 5H-furan-2-ones have been selectively Synthesized by addition of 1,21.6 equiv of aryl, alkenyl or 1-alkynyl halides and catalytic mounts of Pd(OAc)₂ and a soft ligand such as tri-2- furylphosphine or triphenylarsine to

Full text of DOI:10.1016/S0040-4039(98)01652-9

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