Enantioselective reduction of β-keto esters

DOI: 10.1016/S0040-4039(00)92134-8

Source and publish data:

Tetrahedron Letters p. 4227 - 4230 (1991)

Update date:2022-08-17

Topics:

Authors:

Taber, Douglass F.

Silverberg, Lee J.

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Article abstract of DOI:10.1016/S0040-4039(00)92134-8

Highly enantioselective reduction of β-keto esters with BINAP-Ru catalyst can be effected at 50 psig H₂ and 80°, using a Parr shaker. A simplified preparation of the BINAP·Ru catalyst is reported.

Full text of DOI:10.1016/S0040-4039(00)92134-8

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