Tetrahedron Letters p. 7075 - 7078 (1991)
Update date:2022-08-11
Topics:
Nakamura, Kaoru
Kondo, Shin-ichi
Kawai, Yasushi
Ohno, Atsuyoshi
Reduction of α-keto esters by non-immobilized bakers' yeast in an organic solvent is reported.When benzene is employed as the solvent, the reduction tends to afford the corresponding (R)-hydroxy ester predominantly.Key Words: bakers' yeast; asymmetric reduction; organic solvent; stereochemical control; α-keto ester; α-hydroxy ester
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