SYNTHESIS OF 7-CYANO-7-DEAZAGUANINE, ONE OF THE NUCLEOSIDE Q (QUEUOSINE) PRECURSORS FOR THE POST-TRANSCRIPTIONAL MODIFICATION OF tRNA

DOI: 10.1246/cl.1980.559

Source and publish data:

Chemistry Letters p. 559 - 562 (1980)

Update date:2022-08-17

Topics:

Authors:

Kondo, Tadao

Nakatsuka, Shin-ichi

Goto, Toshio

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Article abstract of DOI:10.1246/cl.1980.559

7-Cyano-7-deazaguanine, which is one of the precursors of nucleoside Q (queuosine) biosynthesis, was synthesized from 2-methylthio-6-methoxy-7-methyl-7-diazapurine; methoxymethyl protecting group at 9 position could be removed by transformation to acetoxymethyl group followed by hydrolysis with aq. ammonia.

Full text of DOI:10.1246/cl.1980.559

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