6-Isobutyrylaminopurine: A convenient building block for the synthesis of carbocyclic adenosine analogs

Article abstract of DOI:10.1016/S0040-4039(97)00867-8

Readily available 6-isobutyrylaminopurine can replace either a primary or secondary OH group under Mitsunobu conditions and provide an efficient synthesis of carbocyclic analogs of adenosine. X-ray data indicates that only the desired N⁹-substituted derivatives of adenine are formed.