Helvetica Chimica Acta p. 1012 - 1016 (1986)
Update date:2022-08-28
Topics:
Guggisberg, Armin
Prewo, Roland
Hesse, Manfred
The relative configuration of aphelandrine (1) was established by X-ray structure determination.The absolute configuration of the centers 11 and 18 was determined earlier by chiroptic measurements.Therefore, structure 1 with the configurations 11S, 17S, and 18S represents the absolute configuration of aphelandrine.In the presence of base, 1 was converted to (11S, 17R, 18R)-orantine (2).The 1H-NMR coupling constants between H-C(17) and H-C(18) (part of the dihydrofuran ring) are very much dependent on the substituent pattern of the amino N-atoms N(6) and N(10).
View More
Contact:13357117572
Address:No.149 Shiji dadao Road.
Shanghai Send Pharmaceutical Technology Co., Ltd.
website:http://www.shsendpharma.com
Contact:021-58088081, +8613585868794
Address::Room A601, Building 1,NO. 800 Qingdai Road Pudong District Shanghai,China
Hangzhou Hysen Pharma co.,Ltd.
website:http://www.hysenpharma.cn/
Contact:0086-571-88298791
Address:#701,Gudun Road Hangzhou
Binzhou Holly Pharmaceutical Co.,Ltd.
Contact:74517
Address:No.15 Dapu Road,Huangpu District Shanghai,P.R.China
FOSHAN NANHAI ZHONGNAN PHARMACEUTICAL FACTORY
Contact:0086-0757-85609331
Address:XIAHENGTIAN INDUSTRIAL ZONE,SHAYONG VILLAGE,LISHUI TOWN
Doi:10.1016/j.electacta.2007.03.068
(2007)Doi:10.1016/j.tetasy.2013.10.012
(2013)Doi:10.1002/anie.201606366
(2016)Doi:10.1016/j.molcata.2016.08.021
(2016)Doi:10.1021/acs.joc.7b02634
(2018)Doi:10.1039/c8cc10184a
(2019)
