A NOVEL APPROACH TO THE SYNTHESIS OF DEOXYNUCLEOSIDE PHOSPHOROFLUORIDATES - II.

DOI: 10.1016/0040-4039(88)85146-3

Source and publish data:

Tetrahedron Letters p. 3301 - 3302 (1988)

Update date:2022-08-10

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Authors:

Dabkowski, Wojciech

Cramer, Friedrich

Michalski, Jan

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Article abstract of DOI:10.1016/0040-4039(88)85146-3

Trimethylsilyl esters of general formula RR'POSiMe3 derived from nucleosides react in quantitative and fully chemoselective way with sulphuryl chloride fluoride to give nucleoside fluorophosphates of high purity under extremely mild conditions

Full text of DOI:10.1016/0040-4039(88)85146-3

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