Chemical and Pharmaceutical Bulletin p. 2257 - 2258 (1979)
Update date:2022-08-29
Topics:
Uba
Miyata
Watanabe
Hirobe
Codeine was oxidized to codeinone 7,8-oxide (2) by hydrogen peroxide. Stereospecific reduction of 2 by sodium borhydride afforded codeine 7,8-oxide (3). The configuration of 3 was confirmed by X-ray analysis.
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(2015)
